85-3709-06　Ketoconazole 10g　CAS No:65277-42-1　281105

特徴

• Ketoconazole is an inhibitor of cytochrome P450c17. Enhances the formation of myelin basic protein-positive oligodendrocytes from oligodendrocyte progenitor cells in vitro and promotes remyelination in vivo. Also an antifungal agent. Brain penetrant. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor. Inhibitor of exosome secretion.
• Synonyms:rel-1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]ethanone; cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; (+/-)-Ketoconazole
• Molecular Formula:C26H28Cl2N4O4
• Molecular Weight:531.43
• Purity:≥98%
• Appearance:White to light brown powder
• Melting Point:148-152ºC
• Loss on Drying (80°C, 4hr):≤0.5%
• Solubility:Ethanol, DMSO, Chloroform (Slightly), Methanol (Slightly)
• Storage and Stability:Store at 4ºC. Stable for 6 months after receipt.