85-3622-86　7-Hydroxy Methotrexate 1mg　CAS No:5939-37-7　279142

特徴

• A metabolite of Methotrexate, which is used as a antineoplastic and antirheumatic.
• Synonyms:7-Hydroxy amethopterin, 4-amino-7-hydroxy-10-methylpteroylglutamic acid; N-[4-[[(2,4-Diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid; NSC 380962
• Molecular Formula:C₂₀H₂₂N₈O₆
• Molecular Weight:470.44
• Appearance:Light yellow to light orange solid
• Purity:≥98%
• Melting Point:>221ºC (dec.)
• Solubility:Aqueous Basic (Slightly), DMSO (Slightly, Sonicatedy), Methanol (Slightly)
• Method for Determining Identity:Proton NMR (DMSO-d6, D2O+ NaOD) Spectroscopic and Mass Spectrometric Analysis
• TLC Conditions:C18: Acetonitrile: Water: Ammonium Hydroxide=8:2:0.1; Visualized with UV and KMnO4; Single Spot, Rf=0.40
• Elemental Analysis:Calculated: %C: 51.06, 5H: 4.71, %N: 23.82
• Storage and Stability:Long-term storage is recommended at -20°C. Stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.