85-3274-01　［取扱停止］Deferoxamine Mesylate (NSC 644468) 10g　CAS No:138-14-7　271301

特徴

• An iron chelator used for the treatment of acute iron intoxication and of chronic iron overload due to transfusion-dependent anemias. Has been shown to have anti-proliferative effects on vascular smooth muscle cells in vitro and in vivo and to arrest cells in the G1 phase. Induces apoptosis in HL-60 cells by chelating iron. In addition, it has been shown to have antioxidant properties and to protect cells against H₂O₂-induced damage.
• Synonyms:N1-(5-aminopentyl)-N1-hydroxy-N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]butanediamide methanesulfonate; N-[5-[3-[(5-aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[[5-(N-hydroxyacetamido)pentyl]carbamoyl]propionohydroxamic acid methanesulfonate; Ba 33112; Desferrioxamine B mesylate
• Molecular Formula:C₂₅H₄₈N₆O₈·CH₄O₃S
• Molecular Weight:656.79
• Appearance:White to off-white powder
• Purity:≥95%
• Melting Point:120-125°C
• Solubility:DMSO (Slightly, Heated), Methanol (Slightly, Heated)
• Storage and Stability:Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap