85-2666-25　4-Methylumbelliferyl 2-Acetamido-2-deoxy-b-D-glucopyranoside (GlcNAc1-b-4MU) 500mg　257717

特徴

• Fluorogenic substrate used for the assay of b-Acetylglucosaminidase. A fluorogenic substrate used for the diagnosis of GM2 gangliosidoses in leukocytes. Genetic defects in human b-hexosaminidase isozymes (Hex A & Hex B) result in various clinical and biochemical types of GM2 gangliosidosis. They include Tay Sachs disease, Sandhoff disease and other forms.
• Synonyms:4-Methylumbelliferyl N-acetyl-b-D-glucosaminide; 4-MU-GlcNAc; M3C; GlcNAc-b-4MU
• Molecular Formula:C₁₈H₂₁NO₈
• Molecular Weight:379.36
• Appearance:White to off-white powder
• Purity:≥98% (HPLC)
• Identity (FT-IR):Conforms to structure
• Melting Point:212-214°C
• Specific Optical Rotation [α]D20 (c=1, pyridine):-28 to -32°
• Fluorescence:max. Abs. l = 325nm, max. Em. l = 378nm
• Free 4-MU:≤0.01%
• Water (Karl Fischer):≤1%
• Solubility:Methanol, Warm Water , DMF
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.