85-2629-70　P1 (N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanyl-O-(ethenylsulfonyl)-N-4-pentyn-1-yl-L-tyrosinamide) 1mg　256141

特徴

• Protein disulfide isomerase (PDI) inhibitor (IC50 = 1.7uM). Inhibits proliferation of numerous cancer cell lines. Cell permeable.
• Synonym:N-[(1,1-Dimethylethoxy)carbonyl]-L-phenylalanyl-O-(ethenylsulfonyl)-N-4-pentyn-1-yl-L-tyrosinamide
• Molecular Formula:C30H37N3O7S
• Molecular Weight:583.7
• Appearance:Supplied as a white lyophilized solid.
• Purity:≥98%
• Solubility:Soluble to 100mM in DMSO.
• Solubility Advice:Some solutions can be difficult to obtain and can be encouraged by rapid stirring, sonication or gentle warming (in a 45-60°C water bath).
• Method for Determining Identity:Proton NMR Spectroscopic and Mass Spectrometric analysis
• TLC Conditions:Rf = 0.23 (Ethyl acetate: Petroleum ether (1 : 1))
• Microanalysis:Theoretical:%C: 61.73%H: 6.39%N: 7.2
• Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 6 months after receipt. Light sensitive
• Stock Solutions: Once prepared, aliquot in tightly sealed vials at -20°C or below and used within 1 month. Wherever possible solutions should be made up and used on the same day.
• Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
• Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.