85-2610-95　CEP 1347 1mg　CAS No:156177-65-0　254917

特徴

• Inhibitor of c-jun N-terminal kinase (JNK) signaling. Rescues motor neurons undergoing apoptosis (EC50 = 20nM). Blocks Aβ-induced cortical neuron apoptosis (EC50 ~51nM). Does not inhibit ERK1 activity. Neuroprotective.
• Synonym:(9S,10R,12R)-5-16-Bis[(ethylthio)methyl]-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester
• Molecular Formula:C33H33N3O5S2.1⁄2H2O
• Molecular Weight:624.77
• Purity:≥97% (HPLC)
• Form:Supplied as a white solid
• Solubility:DMSO to 10mM
• Microanalysis:Calculated: %C: 63.44, %H: 5.49, %N: 6.73
• TLC:Rf=0.7 (Dichloromethane: Methanol [9:1])
• Storage and Stability:May be stored at RT for short-term only. Long-term storage is recommended at -20°C for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
• Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.