Emapunil (AC-5216, XBD-173) is a translocator protein, TSPO 18kD ligand.
Target: TSPO ligand XBD173 enhanced gamma-aminobutyric acid-mediated neurotransmission and counteracted induced panic attacks in rodents in the absence of sedation and tolerance development. XBD173 also exerted antipanic activity in humans and, in contrast to benzodiazepines, did not cause sedation or withdrawal symptoms [1]. The selective TSPO ligand, XBD173 exerts anxiolytic effects not only in animal models, but also in human volunteers [2].
Solubility: DMSO ~20mg/ml
1H NMR Spec: Corresponds to that of standard preparationMass Spec: Corresponds to that of standard preparationRetention Tme: Corresponds to that in the chromatogram of standard preparation
