85-2090-82　Boc-Leu-Arg-Arg-AMC (Boc-LRR-AMC, Proteasome Substrate) 5mg　CAS No:109358-46-5 (free base)　226821

特徴

• Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. Substrate for the Kex2 endopeptidase from S. Cervisiae, which has substrate specificity toward the C-terminal side of LR, PR and RR sequences. Can be cleaved by Kallikrein 5 with a P1 site preference for basic residues (R and K). This substrate is useful for inhibitor screening and kinetic analysis.
• Source:Synthetic
• Excitation:Excitation: 380nm. Emission: 460nm.
• Use:Add from DMSO stock directly to in vitro or in vivo assay at desired concentration. Typical concentrations range from 10-100uM.
• Molecular Formula:C33H52N10O7 . HCl
• Molecular Weight:773.8 . 36.5
• Sequence:Boc-Leu-Arg-Arg-7-amido-4-methylcoumarin
• Solubility:5% acetic acid
• Purity:≥98%
• Appearance:Supplied as a solid lyophilized powder.
• Storage and Stability:Stable for at least 1 year after receipt when stored at -20°C.