85-2089-22　Tgm2, Recombinant, Mouse, aa1-686, His-Tag (Transglutaminase-2, Protein-Glutamine Gamma-Glutamyltransferase 2) 500ug　218626

特徴

• Tgm2, also known as protein-glutamine gamma-glutamyltransferase 2, is a calcium dependent enzyme of the protein-glutamine gamma-glutamyltransferases family. Like other transglutaminases, it crosslinks proteins between an epsilon-amino group of a lysine residue and a gamma-carboxamide group of glutamine residue, creating an inter- or intramolecular bond that is highly resistant to proteolysis (protein degradation). Aside from its crosslinking function, tTG catalyzes other types of reactions including deamidation, GTP-binding/hydrolyzing, and isopeptidase activities. unlike other members of the transglutaminase family, tTG can be found both in the intracellular and the extracellular spaces of various types of tissues and is found in many different organs including the heart, the liver, and the small intestine.
• Source:Recombinant protein corresponding to aa1-686 from mouse Tgm2, fused to His-tag at N-terminus, expressed in E.coli.
• Molecular Weight:~79.4kD (709aa)
• Applications:Suitable for use in SDS-PAGE. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.