SPRED1 is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. This protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).
Source:Recombinant protein corresponding to aa1-444 from human SPRED1, fused to His-tag at N-terminus, expressed in E.coli.
Molecular Weight:~52.9kD (467aa)
Applications:Suitable for use in SDS-PAGE. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:50ug
Source Antigen:Recombinant, E. coli
Grade:Purified
Purity:~80% (SDS-PAGE)
Form:Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.