85-2088-33　SIRT1, Recombinant, Human, aa254-495, His-Tag (Sirtuin 1, Sirtuin (Silent Mating Type Information Regulation 2 homolog) 1 (S. cerevisiae), SIR2L1) 100ug　218565

特徴

• SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. Alternative splicing results in multiple transcript variants.
• Source:Recombinant protein corresponding to aa254-495 from human SIRT1, fused to His-tag at N-terminus, expressed in E.coli.
• Molecular Weight:~31.6kD (280aa)
• Applications:Suitable for use in SDS-PAGE. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.