85-2085-48　NDUFS2, Recombinant, Human, aa77-463, His-Tag (NADH Dehydrogenase [Ubiquinone] Iron-Sulfur Protein 2, Mitochondrial Isoform 1 Precursor) 100ug　218392

特徴

• NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform 1 precursor, also known as NDuFS2, is a 463aa protein that is suggested to be required for catalytic activity. Defects in NDuFS2 are the cause of complex I mitochondrial respiratory chain deficiency, which is characterized by a variety of symptoms including liver failure, cardiomyopathy and neurodegeneration. Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation.
• Source:Recombinant corresponding to aa77-463 from human NDuFS2 protein, fused to His-tag at N-terminus, expressed in E.coli.
• Molecular Weight:~46.5kD (410aa)
• Applications:Suitable for use in SDS-PAGE. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.