This protein's function seems to have no role in antigen presentation. It acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. It’s binding to KLRK1 leads to cell lysis.
Source:Recombinant protein corresponding to aa24-297 from human MICA, fused to His-tag at C-terminus, expressed in E.coli.
Molecular Weight:~32.7kD (283aa), confirmed by MALDI-TOF
Applications:Suitable for use in SDS-PAGE. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：50ug
Source Antigen：Recombinant, E. coli
Grade：Purified
Purity：~90% (SDS-PAGE)
Form：Supplied as a liquid in PBS, pH 7.4, 1mM DTT, 10% glycerol.
