85-2083-28　IL12, Recombinant, Human, aa23-328/aa23-219, His-Tag (Interleukin 12 (Subunit beta/alpha)) 20ug　218253

特徴

• IL12 is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. It is a disulfide-linked heterodimer composed of the 40kD cytokine receptor like subunit and a 35kD subunit. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. IL12 has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.
• Source:Recombinant protein corresponding to human IL12, fused to His-tag at C-terminus, expressed in Insect cells.
• Molecular Weight:~34.6kD (p40) & ~23.3kD (p35) (306aa & 203aa) The heterodimeric IL12 has a predicted molecular weight of ~57.9kD (509aa).
• Applications:Suitable for use in SDS-PAGE. Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.