85-2083-25　IGFBP3, Recombinant, Human, aa28-291, His-Tag (Insulin-Like Growth Factor Binding Protein 3 Isoform B Precursor) 500ug　218249

特徴

• IGFBP3 is also known as Insulin-like growth factor binding protein 3 isoform b precursor. They are structurally and functionally related to insulin but have a much higher growth-promoting activity. It may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. It stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. It may play a role in synapse maturation.
• Recombinant protein corresponding to aa28-291 from human IGFBP3, fused to His-tag at N-terminus, expressed in E.coli.
• Molecular Weight:~31kD (285aa)
• Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSHMGASSAGLGP VVRCEPCDAR ALAQCAPPPA VCAELVREPG CGCCLTCALS EGQPCGIYTE RCGSGLRCQPSPDEARPLQA LLDGRGLCVN ASAVSRLRAY LLPAPPAPGN ASESEEDRSA GSVESPSVSS THRVSDPKFH PLHSKIIIIK KGHAKDSQRY KVDYESQSTD TQNFSSESKR ETEYGPCRRE MEDTLNHLKF LNVLSPRGVH IPNCDKKGFY KKKQCRPSKG RKRGFCWCVD KYGQPLPGYT TKGKEDVHCY SMQSK
• Applications:Suitable for use in SDS-PAGE. Other applications not tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.