A potent antagonist for alpha-2-adrenoceptors (pKi values are 8.52, 8.00 and 9.17 for human alpha-2a, alpha-2B and alpha-2C receptors respectively). Often used as pharmacological stressor in animal studies.
Formula:C21H26N2O3 • HCl
Solubility:DMSO
Primary Target:→2-adrenoceptor
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
