A highly potent antagonist selective for mGlu1 receptors (IC50 = 16nM). Biologically active admitted orally or systematically. Often used in assessing the functional roles of mGlu1 receptors in a variety of research areas, such as anxiety and stress related disorders, analgesia, nociceptive pain, and schizophrenia.
Formula:C18H22N4OS•HCl
Solubility:H2O
Primary Target:mGlu1 receptors
Primary Target IC50:16nM
Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.