85-2076-45　RS 102895 Hydrochloride (1’-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4’-piperidin]-2(1H)-one Hydrochloride, RS 102895, RS102895) 5mg　CAS No:300815-41-2　217756

特徴

• A selective antagonist for CCR2 receptors (IC50 = 0.36 and 17.8uM for CCR2b and CCR1 receptors, respectively). Blocks monocyte chemoattractant protein-1 induced calcium influx and chemotaxis (IC50 = 32nM and 1.7uM respectively). A potential anti-inflammatory therapeutic agent by Inhibiting alpha1A, alpha1D and 5-HT1A receptors.
• Synonyms: 1ʹ-[2-[4-(Trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4ʹ-piperidin]-2(1H)-one hydrochloride, RS 102895, RS102895
• Formula:C21H21F3N2O2•HCl
• Solubility:DMSO
• Appearance:Supplied as an off-white powder.
• Primary Target:CCR2
• Primary Target IC50:0.36 and 17.8uM for human recombinant CCR2b and CCR1 receptors, respectively.
• Molecular Weight:426.86
• Storage and Stability:Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

仕様

• Size：5mg
• Grade：Highly Purified
• Purity：≥98% (HPLC)
• Form：Supplied as an off-white powder.
• Molecular Formula：C21H21F3N2O2•HCl
• Molecular Weight Non Ab：426.86
• EU Commodity Code：38220090
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• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：300815-41-2

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