85-2076-43　RORg Inverse Agonist, SR2211 (1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-[1,1'-biphenyl]-4-yl)propan-2-ol, SR-2211, SR 2211) 5mg　CAS No:1359164-11-6　217753

特徴

• A cell-permeable, piperazine containing biphenyl compound that binds directly to retinoic acid receptor related orphan receptor g (RORg) and acts as a highly selective and inverse agonist (Ki =105nM; IC50 ~320nM). Reported to block the transcriptional activity of RORg and suppress the synthesis of IL-17 in EL-4 murine lymphoma cell line. Exhibits only a minimal effect on RORa and LXRa activity.
• Synonyms: 1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-[1,1'-biphenyl]-4-yl)propan-2-ol, SR-2211, SR 2211
• Formula:C₂₆H₂₄F₇N₃O
• Molecular Weight:527.5
• Solubility:DMSO (50mg/ml)
• Form:Supplied as a white powder.
• Storage and Stability:Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

仕様

• Size：5mg
• Grade：Highly Purified
• Purity：≥99% (HPLC)
• Form：Supplied as a white powder.
• Molecular Formula：C₂₆H₂₄F₇N₃O
• Molecular Weight Non Ab：527.5
• EU Commodity Code：38220090
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• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：1359164-11-6

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