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US Biological(nonantibody)
85-2074-87 NF-kappaB Activation Inhibitor X, Methysticin ((6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6- dihydro-4- methoxy-2H-pyraNF-kappaB Activation Inhibitor X, Methysticin ((6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6- dihydro-4- methoxy-2H-pyran-2-one)n-2-one) 5mg 217586
85-2074-87 NF-kappaB Activation Inhibitor X, Methysticin ((6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6- dihydro-4- methoxy-2H-pyraNF-kappaB Activation Inhibitor X, Methysticin ((6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6- dihydro-4- methoxy-2H-pyran-2-one)n-2-one) 5mg CAS No:495-85-2 217586
特徴
Methysticin has been identified from kava to have potent NF-kB inhibitory activity and minimum toxicity. It is shown to inhibit NF-kB (IC50 = 0.19ug/ml) 100 times more potently than traditional kava in A549 cells in an in vitro luciferase-based assay. It is also reported to suppress the elevation of IKKalpha, p65, and COX-2 and the degradation of IkBalpha in A549 cultures stimulated with TNF-alpha; through Western Blot analysis.
Synonyms:(6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6- dihydro-4- methoxy-2H-pyran-2-one
Molecular Formula:C₁₅H₁₄O₅
Solubility:DMSO
Molar Mass:274.27
Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
Size:5mg
Grade:Highly Purified
Purity:≥99% (HPLC)
Form:Supplied as a white solid.
Molecular Formula:C₁₅H₁₄O₅
Molecular Weight Non Ab:274.27
EU Commodity Code:38220090
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CAS No :495-85-2
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