85-2074-81　Nebivolol Hydrochloride (rel-(aR,a’R,2R,2’S)-a,a’-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol] Hydrochloride, b1-Adrenoceptor Antagonist, Nebivolol Hydrochloride, Nebilet, R-65824, Narbivolol) 10mg　CAS No:152520-56-4　217580

特徴

• A competitive, highly selective beta-1-adrenoceptor antagonist (more than 40-fold selective for beta-1 than beta-2; Ki1 and beta-2, respectively). The most beta-1-selective chemical of the beta-blockers tested so far. Used for treatment of essential hypertension and highly cardioselective. Induces mild vasodialation via a nitric oxide- and cGMP-depedent pathways (EC50 = 11.36uM in renal arteries).
• Formula:C22H25F2NO4 • HCl
• Solubility:DMSO
• Primary Target:→1-adrenoceptor
• Primary Target Ki:0.88 and 44 for →1 and →2, respectively
• Molar Mass:441.9
• Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：10mg
• Grade：Highly Purified
• Purity：~98% (HPLC)
• Form：Supplied as a white powder.
• Molecular Formula：C22H25F2NO4 • HCl
• Molecular Weight Non Ab：441.9
• EU Commodity Code：38220090
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• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：152520-56-4

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