A constituent and psychoactive ingredient of the mushroom Amanita muscariathat acts as a potent agonist of GABAA receptors (EC50 = 28uM and 33uM in neonatal and adult rats, respectively), with preferential efficacy and selectivity to high-affinity receptor subtypes. Shown to be permeate the blood-brain barrier. Impairs associate and memory functions.
Molecular Formula:C₄H₆N₂O₂
Solubility:H2O
Primary Target:GABA-A
Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
