A potent agonist of the 5-HT7 serotonin receptor (Ki= 0.22nM) with good selectivity against other 5-HT receptors (5-HT1A Ki = 52.7nM, 5-HT1B Ki = 60nM). Often used in conjuction with the selective 5-HT7 receptor antagonist, SB-269970.
Molecular Formula:C₂₇H₃₈ClN₃OS
Solubility:DMSO or EtOH
Primary Target:5-HT7
Primary Target Ki:0.22nM
Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
