A potent agonist for group II metabotropic glutamate receptors (EC50 = 0.49uM and 0.44uM for mGlu2 and mGlu3, respectively). Higher level of activity than glutamate or (±)-trans-ACPD. Widely used in studies related to neurotransmissions mediated via group II mGlu receptors.
Formula:C6H9NO4
Solubility:Aqueous basic solutions
Primary Target:mGlu2 & mGlu3
Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.