A selective 5-HT2A serotonin receptor antagonist with weak adrenergic receptor blocking properties. Strong affinity for 5-HT2AR (Ki = 1.49nM) relative to other family members like 5-HT2BR (Ki = 740nM) and 5-HT2CR (Ki = 59nM). Often used in conjunction with SB 206553 to distinguish 5-HT2AR and 5-HT2CR activity.
Molecular Formula:C₂₂H₂₂FN₃O₃·C₄H₆O₆
Solubility:DMSO
Primary Target:5-HT2A
Primary Target Ki:1.49nM
Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
