85-2073-38　［取扱停止］Hepatic Differentiation Inducer, SJA710-6 (2-(4-Bromophenyl)-N-(4-fluorophenyl)-3-propyl-3H-imidazo[4,5-b]pyridin-5-amine) 25mg　217417

特徴

• A cell-permeable imidazopyridinamine compound that selectively and potently induces differentiation of mesenchymal stem cells (MSCs) into hepatocyte-like cells (~47% at 5uM). Within 14 days of treatment with SJA710-6, the differentiated cells exhibit typical morphological characteristics of hepatocytes and are able to store glycogen, secret albumin, produce urea, and uptake LDL. Also, shown to increase the mRNA levels of hepatocyte-specific genes, such as albumin, AFP, CK18, c-Met, CYP1A1, CYP2B1, HNF3beta and FoxH1.
• Molecular Formula:C₂₂H₂₀BrFN₄
• Solubility:DMSO
• Molar Mass:439.3
• Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

仕様

• Size：25mg
• Grade：Highly Purified
• Purity：≥98% (HPLC)
• Form：Supplied as a white powder.
• Molecular Formula：C₂₂H₂₀BrFN₄
• Molecular Weight Non Ab：439.3
• EU Commodity Code：38220090
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