85-2073-09　Glucagon-Like Peptide 1 Receptor Agonist 5mg　CAS No:281209-71-0　217385

特徴

• A nonpeptidic quinoxaline compound that acts as a GLP-1R agonist and an allosteric modulator of GLP-1 binding. Shown to induce GLP-1R-mediated cAMP production in BHK plasma membrane preparations (EC50=101nM) and potentiate glucose-dependent insulin release in pancreatic islets derived from wild-type, but not GLP-1R -/-, mice. Unlike GLP-1, its biological activity is not inhibited by orthosteric antagonists such as Exendin.
• Synonyms:6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-, 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB); Compound 2; GLP-1R Agonist
• Molecular Formula:C₁₃H₁₅Cl₂N₃O₂S
• Molecular Weight:348.3
• Purity:≥98% (HPLC)
• Solubility:DMSO (20mg/ml), Ethanol (10mg/ml)
• Storage and Stability:Store at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

仕様

• Size：5mg
• Grade：Highly Purified
• Purity：≥98% (HPLC)
• Form：Yellow solid
• Molecular Formula：C₁₃H₁₅Cl₂N₃O₂S
• Molecular Weight Non Ab：348.3
• EU Commodity Code：38220090
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• 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
• CAS No ：281209-71-0

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