A dibenzofuran conjugated peptidomimetic (13-mer) that acts as an allosteric inhibitor of galectin-1 binding to cell surface glycans (IC50 = 3uM). Shown to reduce the proliferation of endothelial cells and reduce vessel density in murine tumor models.
Molecular Formula:C₈₃H₁₃₂N₁₈O₁₇
Sequence:SVQMKNva-[DBF]-IIVKLNA
Primary Target:Galectin-1
Primary Target IC50:3u
Solubility:DMSO
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.