A potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50 = 0.19-1.66uM and 0.35uM for AMPA and GluK2 receptors, respectively). Routinely used as a tool to distinguish the role of neurotransmissions mediated by AMPA/kainate andnMDA receptors in studying brain functions and disorders.
Molecular Formula:C₈H₂N₄O₆Na₂
Primary Target:AMPA
Primary Target IC50:0.19 to 1.66uM
Secondary Target:GluK2
Solubility:H2O
Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.