A potent agonist selective for neuronal nAChRs (Ki = 2, 5890, 480, 329, and 492nM at alpha4beta2, alpha7, alpha3beta4, alpha6/alpha4beta4, alpha1beta1upsilon-delta, respectively). Clinically used as a smoking cessation medicine and often used in addiction studies.
Primary Target Ki:2, 5890, 480, 329, and 492 nM at &alpha
Purity:≥99% (HPLC)
Appearance:Supplied as a pale yellow solid.
Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
