A highly selective antagonist for NR2B subunit containing nMDA receptors (IC50 = 0.039uM for NR2B and >100uM for NR2A, NR2C, and NR2D). Widely used as neuroprotective, analgesic, antidepressant, and anti-Parkinsonian agent in research.
Formula:C20H25NO3
Solubility:DMSO
Primary Target:NMDA receptors
Primary Target IC50:0.039uM for NR2B and >100uM for NR2A, NR2C, and NR2D
Molar Mass:327.42
Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
