A non-competitive, subunit non-selective, potent antagonist fornMDA receptors (IC50 = 0.13, 0.068, 0.087, and 0.14uM for NR2A - D, respectively). Widely used as neuroprotective agent after acute traumatic brain injury and stroke in animal researches.
Formula:C20H21N3 • HCl
Solubility:H2O
Primary Target:NMDA receptors
Primary Target IC50:0.13, 0.068, 0.087, and 0.14uM for NR2A –D, respectively.
Molar Mass:339.86
Storage and Stability:May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
