85-2071-14　［受注停止］Adenosine A2A Receptor Antagonist II, SCH-58261 (2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, SCH58261, SCH 58261) 10mg　217152

特徴

• A highly potent and selective antagonist of adenosine A2A receptor (Ki = 600pM). Does not affect the activity of other adenosine receptors in any significant manner (Ki = 287nM; 5uM, and > 10uM for A1, A2B, and A3 receptors, respectively). Displays neuroprotective effects in cerebral ischaemia in rats, and shown to counteract Parkinsonian-like muscle rigidity in rats.
• Synonyms:2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, SCH58261, SCH 58261
• Solubility:H2O
• Molecular Formula:C₁₈H₁₅N₇O
• Primary Target:A2A Receptor
• Primary Target Ki:600pM
• Storage and Stability:Store at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
• Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.