A cell-permeable and reversible inhibitor of protein kinase A (Ki = 11uM). Resistant to hydrolysis by phosphodiesterases. Noncompetitive with respect to ATP.
Formula:C10H11N5O5PS · (CH3CH2)3NH
Solubility:H2O (20mg/ml)
Molecular Weight:446.5
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
