A very potent, water-soluble antagonist of the nMDA receptors complex acting at the strychnine-insensitive glycine binding site (IC50 = 0.56uM). Also a potent inhibitor of glutamate transporter. Often used in studies of neuroprotection and schizophrenia.
Synonyms:7-Chloro-4-hydroxyquinoline-2-carbo-xylic acid sodium salt
Molecular Weight:245.6
Formula:C10H5ClNNaO3
Solubility:H2O
Primary Target:NMDA receptors
Primary Target IC50:0.56 →M
Storage and Stability:Store at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
