Prolactin (PRL), also known as luteotropic hormone (LTH), is a neuroendocrine hormone and member of the somatotropin/prolactin family, which is secreted by the anterior pituitary, under the regulation of neuroendocrine neurons in the hypothalamus. The primary function of prolactin is the stimulation of breast development, and promotion of lactation during pregnancy and suckling, but prolactin also exhibits a weak luteotropic effect. Elevated levels of prolactin can be associated with hypothalamic disease, hypothyroidism, kidney disease, chest wall trauma or irritation, and tumors of the pituitary, including prolactinomas.
Source:Recombinant protein corresponding to human prolactin expressed in E. coli.
Molecular Weight:~23kD (200aa residues)
Biological Activity:Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0ng/ml.
Applications:Suitable for use in Functional Assays. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Endotoxin: <1EU/ug
Storage and Stability:Lyophilized powder may be stored at -20°C. Reconstitute with 500ul sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：50ug
Source Antigen：Recombinant, E. coli
Grade：Highly Purified
Purity：~98% (SDS-PAGE, HPLC)
Form：Supplied as a lyophilized powder. No preservative added. Reconstitute with 500ul sterile dH2O.
