Inhibin beta B, otherwise known as Activin B, is a member of the transforming growth factor-beta (TGF-B) family, which signals through the ActRII receptor (Activin Receptor type II), and acts as a regulator of hormone secretion from the pituitary, hypothalamic and gonadal glands. Inhibin beta B is a homodimer of the inhibin/activin beta-B chain, and is involved in several aspects of embryonic development, as well as haematopoiesis and osteogenesis, and also acts as a modulator of FSH (follicle-stimulating hormone) secretion and haemoglobin synthesis.
Source:Recombinant protein corresponding to human Inhibin beta B expressed in High-5 insect cells.
Molecular Weight:~25.6kD (115aa beta B homodimer)
Biological Activity:The ED50 as determined by its ability to inhibit the proliferation of murine MPC11 cells is <2ng/ml, corresponding to a specific activity of >5x10e5units/mg.
Applications:Suitable for use in Functional Assays. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Endotoxin Level: <1EU/ug
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with 10mM sodium citrate. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：5ug
Source Antigen：Recombinant, High-5 insect cells
Grade：Highly Purified
Purity：~95% (SDS-PAGE, HPLC)
Form：Supplied as a lyophilized powder in 10mM sodium citrate, 5% trehalose. Reconstitute with 10ul 10mM sodium citrate, pH 3.
