Influenza is an acute infection of the respiratory tract caused by the Influenza virus, of which there are several different types. Influenza A causes flu in birds and some mammals and is the most virulent of the influenza types, resulting in the most severe disease. Influenza infection in humans causes chills, fever, pharyngitis, muscle pain, headaches, coughing and weakness. The virus is transmitted through the air by coughs or sneezes or through saliva, nasal secretions, faeces and blood. Infection may occur through direct contact with infected bodily fluid or contaminated surfaces. Influenza viruses mutate rapidly, making vaccines less effective from one season to the next. This particular strain of influenza is a reassortant virus that includes genetic components of the H1N1 influenza pandemic swine flu in a culture-adapted virus that has been selected for its qualities as a vaccine-producing strain. The live reassortant virus has passed safety testing in ferrets, in which it is attenuated for pathogenicity relative to wild-type A/California/4/2009 virus. Because A/California/4/2009 is identified as a variant strain of a pandemic virus, live derivatives must be handled under BSL2+ facilities and procedures. This product contains a high concentration of viral antigens as well as some egg proteins from allantoic fluid. Hemaglutination endpoint assay; 11,000 HA Units/ml
Activity:This product has been rendered inactive by standard procedures. However this material should still be handled as infectious and should be disposed of appropriately.
HA Titer:40320 HA Units/mL
Applications:Suitable for use in ELISA and Haemagglutination. Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
