Annexin II (ANXA2), otherwise known as Lipocortin II, is a pleiotropic calcium-dependent phospholipid-binding protein and member of the annexin family, which acts as an autocrine factor, enhancing the formation of osteoclasts and resorption of bone, and is implicated in both exocytosis and endocytosis. ANXA2 is a substrate for both tyrosine and serine/threonine kinases, and is phosphorylated following growth factor stimulation and cellular activation by viral transformation.
Source:Recombinant protein corresponding to human ANXA2, fused to 6xHis-tag expressed in E. coli
Molecular Weight:~41.3kD (361aa residues with tag)
Applications:Suitable for use in ELISA, Western Blot. Other applications not tested.
Recommended Dilution:Western Blot: 1-5ug/laneOptimal dilutions to be determined by the researcher.
Endotoxin: <0.1ng/ug
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:25ug
Source Antigen:Recombinant, E. coli
Grade:Purified
Purity:Purified
Form:Supplied as a liquid in PBS. No preservative added.