Streptokinase is an extracellular metallo-enzyme produced by beta-haemolytic streptococcus and is used as an effective and cheap clot-dissolving medication in some cases of myocardial infarction (heart attack) and pulmonary embolism. It belongs to a group of medications known as fibrinolytics, and works by activating plasminogen through cleavage to produce plasmin.
Source:Recombinant protein corresponding to a non-glycosylated polypeptide chain containing 414aa from Streptokinase, expressed in E. coli.
Molecular Weight:~47kD
Biological Activity:One unit will liquefy a standard clot of fibrinogen, plasminogen and thrombin at pH 7.5 at 37°C in 10 min.
Storage and Stability:Lyophilized powder may be stored at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：250KU
Source Antigen：Recombinant, E. coli
Grade：Highly Purified
Purity：~98% (RP-HPLC, SDS-PAGE)
Form：Supplied as a lyophilized powder in 12.5mg HSA, 2.3mg sodium phosphate dibasic, 0.55mg sodium phosphate monobasic, 4.2mg sodium glutamate monohydrate. Reconstitute with 100ul ddH2O for ~1mg/ml stock
