Chemokine (C-C motif) ligand 18 (CCL18) is a small cytokine belonging to the CC chemokine family that was previouslycalled PARC (pulmonary and activation-regulated chemokine). CCL18 is ~60% identical in amino acid sequence to CCL3. It is expressed at high levels in lung and at lower levels in certain lymphoid tissues, such as the lymph nodes, and is chemotactic for activated T cells and nonactivated lymphocytes. The gene for human CCL18 contains three exons and is located on chromosome 17.
Source:Recombinant protein corresponding to a single, non-glycosylated, polypeptide chain containing 69aa from human MIP4, expressed in E. coli.
Molecular Weight:~7.8kD
Biological Activity:Calculated by the ability to chemoattract human T lymphocytes at 1-10ng/ml.
Storage and Stability:Lyophilized powder may be stored at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：10ug
Source Antigen：Recombinant, E. coli
Grade：Highly Purified
Purity：~97% (RP-HPLC, SDS-PAGE)
Form：Supplied as a lyophilized powder in 20mM PBS, pH 7.4, 100mM sodium chloride. Reconstitute with 100ul sterile ddH2O for ~1mg/ml stock. For long term storage add a carrier protein (0.1% HSA or BSA).
