LAIR-1 is a glycoprotein (~32kD) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Inhibitory receptors control the immune response to prevent lysis of cells recognized as self. Lair1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region.
Source:Recombinant protein corresponding to human LAIR-1, a single, non-glycosylated polypeptide chain containing 105aa, expressed in E. coli. The extracellular domain of LAIR-1 (aa22-125) was overexpressed in E. coli.
Molecular Weight:~11.5kD
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：5ug
Source Antigen：Recombinant, E. coli
Grade：Highly Purified
Purity：~95% (RP-HPLC, SDS-PAGE)
Form：Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 50mM sodium chloride, 1mM EDTA.
