The GAGA factor is a sequence-specific DNA-binding protein, which participates in the regulation of the expression of a variety of different classes of genes in Drosophila such as many developmentally regulated genes, stress induced genes, and cell cycle regulated genes, as well as housekeeping genes. GAGA contains a C-terminal glutamine-rich domain and a highly conserved N-terminal POZ domain which reported to be involved in self-oligomerization in a number of other POZ domain containing proteins. In case of GAGA protein, the N-terminal POZdomain mediates the formation of oligomers both in vitro and in vivo.
Source:Recombinant protein corresponding to Drosophila melanogaster GAGA-POZ, a single, non-glycosylated polypeptide chain containing 130aa, expressed in E. coli.
Molecular Weight:~14kD
Storage and Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:10ug
Source Antigen:Recombinant, E. coli
Grade:Highly Purified
Purity:~95% (RP-HPLC, SDS-PAGE)
Form:Supplied as a liquid in 10mM HEPES, pH 7.4, 25mM sodium chloride.