Myelin Oligodendrocyte Glycoprotein is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a prime target antigen that plays a role in immune-mediated demyelination. Myelin Oligodendrocyte Glycoprotein is involved in completion and maintenance of the myelin sheath and in cell-cell communication. MOG protein was found to differentially expressed in the dorsolateral prefrontal cortex and in the temporal lobe from patients with schizophrenia. MOG-specific antibody iscrucial to the initiation of MOG-induced mouse experimental autoimmune encephalomyelitis.
Source:Recombinant protein corresponding to human CD14, a single, non-glycosylated polypeptide chain containing 132aa, fused to 6xHis-tag at C-terminus, expressed in E. coli.
Molecular Weight:~15.2kD
Applications:Suitable for use in ELISA, Western Blot, T-cell proliferation, cytokine induction, antigen presentation, and EAE induction in mice. Other applications not tested.
Recommended Dilution:In-Vitro Experiments: 5-20ug/mlIn-Vivo Studies: 50-100ug/animalOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size：2ug
Source Antigen：Recombinant, E. coli
Grade：Purified
Purity：Purified
Form：Supplied as a lyophilized powder in 20mM sodium acetate, pH 4.0, 0.3M sodium chloride. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
