PARP-2 [ARTD2] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modi- fication follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Source:Recombinant protein corresponding to full-length mouse PARP-2, fused to a His-tag, expressed in Sf21 cells.
Biological Activity:≥600U/mg protein
Storage and Stability:Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:10ug
Source Antigen:Recombinant, Sf21 cells
Grade:Highly Purified
Purity:≥98% (SDS-PAGE)
Form:Supplied as a liquid in 50mM TRIS-HCl, pH 7.5, 100mM sodium chloride, 50mM imidazole, 0.2% NP-40, 10% glycerol.