85-2061-05　Nargenicin A1 5mg　207295

特徴

• Antibiotic against Gram-positive bacteria, particularly Staphylococcus and Clostridia. More effective against multi-resistant strains (MRSA) than erythromycin and vancomycin. Inhibits cell proliferation and induces HL-60 cell differentiation in combination with 1,25-Dihydroxyvitamin-D3 and ATRA. Displays low cytotoxicity compared to erythromycin and spiramycin.
• Alternate Names:Antibiotic 47444; CP 47444; NSC 355066; Nargenicin; Nargenicin A1; Stereoisomer of 3,4,6,7,8,8a,10a,11,12,13,14,14a-dodecahydro-14-hydroxy-4-(1-hydroxyethyl)-7-methoxy-1,3,13-trimethyl-6-oxo-11,14b-epoxy-14bH-naphth[2,1-e]oxecin-12-yl 1H-pyrrole-2-carboxylate; [3R-[1E,3R*,4S*(R*),7S*,8aS*,10aR*,11R*,12R*,13R*,14R*,14aS*,14bS*]]-1H-Pyrrole-2-carboxylic acid 3,4,6,7,8,8a,10a,11,12,13,14,14a-Decahydro-14-hydroxy-4-(1-hydroxyethyl)-7-methoxy-1,3,13-trimethyl-6-oxo-11,14b-epoxy-14bH-naphth[2,1-e]oxecin-12-yl Ester; 9-(1H-Pyrrole-2-carboxylate) Nodusmicin
• Source:Actinomyces sp. Gö301
• Molecular Formula:C₂₈H₃₇NO₈
• Solubility:DMSO or methanol
• Molecular Weight:515.6
• Method for Determining Identity:Proton NMR
• Purity:≥98% (HPLC)
• Appearance:Off-white powder
• Storage and Stability:May be stored at 4°C for short-term only. Long-term storage is recommended at -20°C. Stable for 1 year after receipt. Protect from light when in solution. For maximum recovery of product, centrifuge the original vial prior to removing the cap.