Antileishmanial agent. Active against Leishmania donovani, the causative agent of visceral leishmaniasis. Showed no activity against intracellular Leishmania. Isatropolone A is an amine-reactive fluorescent compound. Cytostatic and weak cytotoxic (3-10uM).
Source:Streptomyces rubiginosohelvolus Gö66
Formula:C24H24O9
Solubility:DMSO, chloroform or dichloromethane
Molecular Weight:~456.5
Method for Determining Identity:Proton NMR
Purity:≥98% (HPLC)
Form:Supplied as an orange powder.
Storage and Stability:May be stored at 4°C for short-term only. Long-term storage is recommended at -20°C. Stable for 1 year after receipt. Protect from light when in solution. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
