Receptor for interleukin-33 (IL-33). Its stimulation recruits MYD88, IRAK1, IRAK4 and TRAF6 followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14 and MAPK8 by similarity. Possibly involved in helper T cell function.
Source:Recombinant protein corresponding to aa19-328 from human IL-33R, fused to the N-terminus of the Fc region, expressed in CHO cells.
Biological Activity:Measured by its ability to bind recombinant human IL-33 in a functional ELISA.
Endotoxin:<0.06EU/ug protein (LAL test; Lonza)
Storage and Stability:Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
仕様
Size:50ug
Source Antigen:Recombinant, CHO cells
Grade:Highly Purified
Purity:≥98% (SDS-PAGE)
Form:Supplied as a lyophilized powder in PBS. Reconstitute with 50ul sterile PBS.