85-2060-46　Hypothemycin 250ug　CAS No:76958-67-3　207223

特徴

• Antifungal. Cytotoxic against some tumor cell lines, partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells. Modulates production of cytokines during T cell activation. Facilitates the ubiquitinylation process of cyclin D1. Potent and selective threonine/tyrosine-specific kinase, MEK and other protein kinases inhibitor in both in vitro and in vivo studies.
• Synonyms:3H-Oxireno[k][2]benzoxacyclotetradecin-5,11(2H,4H)-dione,1a,8,9,15b-tetrahydro-3,4,12-trihydroxy-14-methoxy-9-methyl-,(1aR,3S,4S,6Z,9S,15bR)-, NSC354462
• Source:Phoma sp.
• Molecular Formula:C₁₉H₂₂O₈
• Solubility:Soluble in DMSO or acetone; insoluble in methanol or H2O.
• Molecular Weight:378.4
• Method for Determining Identity:Proton NMR
• Purity:≥98% (HPLC)
• Appearance:Supplied as a white to off-white solid.
• Storage and Stability:Store at -20°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.