85-2060-25　Ganglioside GQ1b, Bovine (Tetrasialoganglioside GQ1b, GQ1b•4Na) 500ug　207204

特徴

• Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GQ1b specifically promotes neural differentiation of human neuroblastoma cells. Anti-GQ1b antibodies are present in serum from Miller-Fisher syndrome patients.
• Source:Bovine brain
• Sequence:IV3Neu5Ac2II3NeuAc2GgOse4Cer;alpha-Neu5Ac-(2-8)-alpha-Neu5Ac-(2-3)-beta-Gal-(1-3)-beta-GalNAc-(1-4)-[alpha-Neu5Ac-(2-8)-alpha-Neu5Ac-(2-3)-]beta-Gal-(1-4)-beta-Glc-(1-1)-Cer
• Reconstitution:Reconstitute in water (micellar aggregates) or Chloroform:Methanol (2:1).
• Molecular Weight:~2416.6, 92.0 (calculated on sphingosine C18:1 and stearic acid)
• Storage and Stability:Powder may be stored at -20°C. Stable for 6 months after receipt at -20°C. Hygroscopic. Keep tightly closed and desiccated.